The AIDS epidemic has had a devastating impact on child survival in sub-Saharan Africa. In Botswana, under-five mortality almost doubled from 1990 to 2000. Since then, remarkable progress has been made to prevent pregnant HIV-positive mothers from passing the virus to their infants, either in utero or through breastfeeding. Yet in a study published this July in BMC Pediatrics, Harvard AIDS Initiative (HAI) researchers found that HIV-exposed or infected children in Botswana account for more than half of deaths in children younger than two. Continue reading →
Missed the Conference on Retroviruses and Opportunistic Infections (CROI) in Boston, February 22-25, 2016? No worries. You can still view videos of major HAI/BHP presentations and press conferences. Continue reading →
Congratulations to Roger Shapiro, a key member of the Harvard AIDS Initiative team, for his recent appointment as an Associate Professor of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health. In the announcement letter below, Dean Frenk lays out Shapiro’s research accomplishments to date.
Should babies infected with HIV in utero be put on anti-HIV drugs immediately after birth? Can very early treatment allow some children to eventually control the virus on their own? HAI researchers are helping to answer those questions. Continue reading →
Imagine that you’re a young woman in southern Africa, giving birth to the child you’ve carried for nine months. Between the pain and the pushing, you feel both excitement and dread. At the antenatal clinic several months ago, you learned that you were infected with HIV. The doctor gave you antiretroviral (ARV) drugs to prevent your child from being born with HIV. You pray that they worked.
The Mma Bana Study, led by Dr. Roger Shapiro, an infectious disease specialist at the Harvard AIDS Initiative (HAI), compared three different drug regimens to prevent mother-to-child transmission of HIV though pregnancy, delivery and six months of breastfeeding. Continue reading →
There are not many couples in which both husband and wife are first authors on a paper in the prestigious New England Journal of Medicine, but Drs.Roger Shapiro and Shahin Lockman are one of them. In addition to being researchers for the Harvard AIDS Initiative, both are also physicians specializing in infectious diseases. Together they have three sons, ages three, six and nine. And in spite of constant demands on their schedules, Shapiro and Lockman spend a significant amount of time mentoring young HIV/AIDS researchers.