The Inner Life of a Complex Clinical Trial

Team Meeting at the BHP Photo By Dominic Chavez

Sent: October 30, 2013 Subject: YA TSIE-In the Field Hi, This is to confirm that the YA TSIE Study—The Botswana Combination Prevention Project (BCPP) is underway and the team deployed today 30th October in the field at both Ranaka and Digawana. While there have been challenges and some initial delay in study initiation, it is with great confidence in the team and their ability to rise up to challenges that…

Morgan Packer: Doing What Needs to Get Done

  Loading file cabinets onto a truck in Lobatse, Botswana wasn’t in Morgan Packers’ job description. Neither was pressing contractors to bring renovations up to code at the Nyangabgwe Hospital Clinic, but unhesitatingly, she did both. “She’s someone you trust to do a job well and on time,” said Dr. Shahin Lockman, one of Morgan’s mentors. “She’s resourceful, adaptable, and has the ability to work with new people in a…

The Forum: Treatment As Prevention

Can We Treat Our Way Out of the AIDS Epidemic? With no cure or vaccine in sight, HIV/AIDS remains a devastating epidemic, particularly in sub-Saharan Africa where nearly 70% of new HIV infections occur. To curb HIV/AIDS, researchers have proposed a strategy to use drug treatment to decrease new transmissions so much that the epidemic eventually dies out. The concept requires changes in standards of when anti-retroviral therapy begins and…

HEU Infants: How Big and Bad Is the Problem?

By Martha Henry Imagine that you’re a young woman in southern Africa, giving birth to the child you’ve carried for nine months. Between the pain and the pushing, you feel both excitement and dread. At the antenatal clinic several months ago, you learned that you were infected with HIV. The doctor gave you antiretroviral (ARV) drugs to prevent your child from being born with HIV. You pray that they worked.

Drs. Roger Shapiro & Shahin Lockman: Partners in Research & Parenting

Shahin Lockman and Roger Shapiro

By Martha Henry There are not many couples in which both husband and wife are first authors on a paper in the prestigious New England Journal of Medicine, but Drs.Roger Shapiro and Shahin Lockman are one of them. In addition to being researchers for the Harvard AIDS Initiative, both are also physicians specializing in infectious diseases. Together they have three sons, ages three, six and nine. And in spite of…