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Moyo S, Gaseitsiwe S, Mohammed T, Pretorius Holme M, Wang R, Kotokwe KP, Boleo C, Mupfumi L, Yankinda EK, Chakalisa U, van Widenfelt E, Gaolathe T, Mmalane MO, Dryden-Peterson S, Mine M, Lebelonyane R, Bennett K, Leidner J, Wirth KE, Tchetgen Tchetgen E, Powis K, Moore J, Clarke WA, Lockman S, Makhema JM, Essex M, Novitsky V. Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015. PLoS One. 2018 Oct 24.
Ajibola G, Leidner J, Mayondi GK, van Widenfelt E, Madidimalo T, Petlo C, Moyo S, Mmalane M, Williams PL, Cassidy AR, Shapiro R, Kammerer B, Lockman S. HIV Exposure and Formula Feeding Predict Under-2 Mortality in HIV-Uninfected Children, Botswana. J Pediatr. 2018 Oct 11.
Anderson M, Choga WT, Moyo S, Bell TG, Mbangiwa T, Phinius BB, Bhebhe L, Sebunya TK, Lockman S, Marlink R, Kramvis A, Essex M, Musonda RM, Blackard JT, Gaseitsiwe S. Molecular Characterization of Near Full-Length Genomes of Hepatitis B Virus Isolated from Predominantly HIV Infected Individuals in Botswana. Genes (Basel). 2018 Sep 7.
Lockman S, De Gruttola V. Outcomes following pregnancy conception on ART: a call for more data. Clin Infect Dis. 2018 Aug 22.
Anderson M, Choga WT, Moyo S, Bell TG, Mbangiwa T, Phinius BB, Bhebhe L, Sebunya TK, Makhema J, Marlink R, Kramvis A, Essex M, Musonda RM, Blackard JT, Gaseitsiwe S. In Silico Analysis of Hepatitis B Virus Occult Associated Mutations in Botswana Using a Novel Algorithm. Genes (Basel). 2018 Aug 21.
Zash R, Makhema J, Shapiro RL. Neural-Tube Defects with Dolutegravir Treatment from the Time of Conception. N Engl J Med. 2018 Jul 24.
Stringer EM, Kendall MA, Lockman S, Campbell TB, Nielsen-Saines K, Sawe F, Cu-Uvin S, Wu X, Currier JS. Pregnancy outcomes among HIV-infected women who conceived on antiretroviral therapy. PLoS One. 2018 Jul 18.
Temfack E, Bigna JJ, Luma HN, Spijker R, Meintjes G, Jarvis JN, Dromer F, Harrison T, Cohen JF, Lortholary O. Impact of routine cryptococcal antigen screening and targeted pre-emptive fluconazole therapy in antiretroviral naive HIV-infected adults with less than 100 CD4 cells/μL: a systematic review and meta-analysis. Clin Infect Dis. 2018 Jul 18.
Kacanek D, Williams PL, Mayondi G, Holding P, Leidner J, Moabi K, Tepper V, Nichols S, Makhema J, Jibril H, Maididimalo T, Shapiro R, Lockman S, Kammerer B. Pediatric Neurodevelopmental Functioning Following in utero Exposure to Triple-NRTI vs. Dual-NRTI + PI ART in a Randomized Trial, Botswana. J Acquir Immune Defic Syndr. 2018 Jul 10.
Ojwach DBA, MacMillan D, Reddy T, Novitsky V, Brumme ZL, Brockman MA, Ndung’u T, Mann JK. Pol-driven replicative capacity impacts disease progression in HIV-1 subtype C infection. J Virol. 2018 Jul 11.
Jarvis JN, Leeme TB, Molefi M, Chofle AA, Bidwell G, Tsholo K, Tlhako N, Mawoko N, Patel RKK, Tenforde MW, Muthoga C, Bisson GP, Kidola J, Changalucha J, Lawrence D, Jaffar S, Hope W, Molloy SLF, Harrison TS. Short Course High-dose Liposomal Amphotericin B for HIV-associated Cryptococcal Meningitis: A phase-II Randomized Controlled Trial. Clin Infect Dis. 2018 Jun 26.
Seatla KK, Avalos A, Moyo S, Mine M, Diphoko T, Mosepele M, Gaolatlhe T, Rowley CF, Ramaabya D, Jarvis JN, Kasvosve I, Gaseitsiwe S. Four class drug resistant HIV-1 subtype C in a treatment experienced individual on dolutegravir based antiretroviral therapy in Botswana. AIDS. 2018 Jun 11.
Tapela NM, Peluso MJ, Kohler RE, Setlhako II, Botebele K, Gabegwe K, Nkele I, Narasimhamurthy M, Mmalane M, Grover S, Barak T, Shulman LN, Lockman S, Dryden-Peterson S. A Step Toward Timely Referral and Early Diagnosis of Cancer: Implementation and Impact on Knowledge of a Primary Care-Based Training Program in Botswana. Front Oncol. 2018 May 29;8:187.
Slogrove AL, Becquet R, Chadwick EG, Côté HCF, Essajee S, Hazra R, Leroy V, Mahy M, Murenga M, Wambui Mwangi J, Oyiengo L, Rollins N, Penazzato M, Seage GR 3rd, Serghides L, Vicari M, Powis KM. Surviving and Thriving-Shifting the Public Health Response to HIV-Exposed Uninfected Children: Report of the 3rd HIV-Exposed Uninfected Child Workshop. Front Pediatr. 2018 May 30;6:157
Zash R, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Gaolethe T, Petlo C, Lockman S, Holmes LB, Makhema J, Shapiro RL. Comparative safety of dolutegravir-based or efavirenz-based antiretroviral treatment started during pregnancy in Botswana: an observational study. Lancet Glob Health. 2018 Jun 4.
Ibrahim M, Maswabi K, Ajibola G, Moyo S, Hughes MD, Batlang O, Sakoi M, Auletta-Young C, Vaughan L, Lockman S, Jean-Philippe P, Yu X, Lichterfeld M, Kuritzkes DR, Makhema J, Shapiro RL. Targeted HIV testing at birth supported by low and predictable mother-to-child transmission risk in Botswana. J Int AIDS Soc. 2018 May.
Mbangiwa T, Kasvosve I, Anderson M, Thami PK, Choga WT, Needleman A, Phinius BB, Moyo S, Leteane M, Leidner J, Blackard JT, Mayondi G, Kammerer B, Musonda RM, Essex M, Lockman S, Gaseitsiwe S. Chronic and Occult Hepatitis B Virus Infection in Pregnant Women in Botswana. Genes (Basel). 2018 May 17.
Mosepele M, Mohammed T, Mupfumi L, Moyo S, Bennett K, Lockman S, Hemphill LC, Triant VA. HIV disease is associated with increased biomarkers of endothelial dysfunction despite viral suppression on long-term antiretroviral therapy in Botswana. Cardiovasc J Afr. 2018 May 14.
Moyo S, Gaseitsiwe S, Powis KM, Pretorius Holme M, Mohammed T, Zahralban-Steele M, Yankinde EK, Maphorisa C, Abrams W, Lebelonyane R, Manyake K, Sekoto T, Mmalane M, Gaolathe T, Wirth KE, Makhema J, Lockman S, Clarke W, Essex M, Novitsky V. Undisclosed antiretroviral drug use in Botswana: implication for national estimates. AIDS. 2018 May 11.
Diphoko T, Gaseitsiwe S, Kasvosve I, Moyo S, Okatch H, Musonda R, Wainberg MA, Makhema J, Marlink R, Novitsky V, Essex M. Prevalence of Rilpivirine and Etravirine resistance mutations in HIV-1 Subtype C- infected patients failing Nevirapine or Efavirenz-based combination antiretroviral therapy in Botswana. AIDS Res Hum Retroviruses. 2018 May 6.
Novitsky V, Gaolathe T, Mmalane M, Moyo S, Chakalisa U, Kadima Yankinda E, Marukutira T, Pretorius Holme M, Sekoto T, Gaseitsiwe S, Musonda R, van Widenfelt E, Powis KM, Khan N, Dryden-Peterson S, Bennett K, Wirth KE, Tchetgen Tchetgen E, Bachanas P, Mills LA, Lebelonyane R, Shenaaz EH, Makhema J, Lockman S, Essex M. Lack of Virological Suppression among Young HIV-Positive Adults in Botswana. J Acquir Immune Defic Syndr. 2018 Apr 27.
Zash R, Rough K, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Petlo C, Lockman S, Makhema J, Shapiro RL. Effect of Gestational Age at Tenofovir-Emtricitabine-Efavirenz Initiation on Adverse Birth Outcomes in Botswana. J Pediatric Infect Dis Soc. 2018 Apr 23.
Mallampati D, MacLean RL, Shapiro R, Dabis F, Engelsmann B, Freedberg KA, Leroy V, Lockman S, Walensky R, Rollins N, Ciaranello A. Optimal breastfeeding durations for HIV-exposed infants: the impact of maternal ART use, infant mortality and replacement feeding risk. J Int AIDS Soc. 2018 Apr.
Powis KM, Lockman S, Ajibola G, Hughes MD, Bennett K, Leidner J, Batlang O, Botebele K, Moyo S, van Widenfelt E, Makhema J, Petlo C, Jibril HB, McIntosh K, Essex M, Shapiro RL. Similar HIV protection from four weeks of zidovudine versus nevirapine prophylaxis among formula-fed infants in Botswana. South Afr J HIV Med. 2018 Mar 28.
Chaudhury S, Mayondi GK, Williams PL, Leidner J, Shapiro R, Diseko M, Ajibola G, Holding P, Tepper V, Makhema J, Petlo C, Seage GR 3rd, Lockman S, Kammerer B. In utero exposure to antiretrovirals and neurodevelopment among HIV-exposed uninfected children in Botswana. AIDS. 2018 Mar 15.
Marukutira T, Stoové M, Lockman S, Mills LA, Gaolathe T, Lebelonyane R, Jarvis JN, Kelly SL, Wilson DP, Luchters S, Crowe SM, Hellard M. A tale of two countries: progress towards UNAIDS 90-90-90 targets in Botswana and Australia. J Int AIDS Soc. 2018 Mar.
Weinberg A, Lindsey J, Bosch R, Persaud D, Sato P, Ogwu A, Asmelash A, Bwakura-Dangarambezi M, Chi BH, Canniff J, Lockman S, Gaseitsiwe S, Moyo S, Smith CE, Moraka NO, Levin MJ; P1072 and Tshipidi Study Teams. B and T Cell Phenotypic Profiles of African HIV-Infected and HIV-Exposed Uninfected Infants: Associations with Antibody Responses to the Pentavalent Rotavirus Vaccine. Front Immunol. 2018 Jan 19.
Mupfumi L, Moyo S, Molebatsi K, Thami PK, Anderson M, Mogashoa T, Iketleng T, Makhema J, Marlink R, Kasvosve I, Essex M, Musonda RM, Gaseitsiwe S. Immunological non-response and low hemoglobin levels are predictors of incident tuberculosis among HIV-infected individuals on Truvada-based therapy in Botswana. PLoS One. 2018 Jan 31.
Arikawa S, Rollins N, Jourdain G, Humphrey J, Kourtis AP, Hoffman I, Essex M, Farley T, Coovadia HM, Gray G, Kuhn L, Shapiro R, Leroy V, Bollinger RC, Onyango-Makumbi C, Lockman S, Marquez C, Doherty T, Dabis F, Mandelbrot L, Le Coeur S, Rolland M, Joly P, Newell ML, Becquet R. Contribution of maternal ART and breastfeeding to 24-month survival in HIV-exposed uninfected children: an individual pooled analysis of African and Asian studies. Clin Infect Dis. 2017 Dec 21.
Novitsky V, Prague M, Moyo S, Gaolathe T, Mmalane M, Kadima Yankinda E, Chakalisa U, Lebelonyane R, Khan N, Powis KM, Widenfelt E, Gaseitsiwe S, Dryden-Peterson SL, Pretorius Holme M, De Gruttola V, Bachanas P, Makhema J, Lockman S, Essex M. High HIV-1 RNA among Newly Diagnosed People in Botswana. AIDS Res Hum Retroviruses. 2017 Dec 7.
Rantshabeng PS, Moyo S, Moraka NO, Ndlovu A, MacLeod IJ, Gaseitsiwe S, Kasvosve I. Prevalence of oncogenic human papillomavirus genotypes in patients diagnosed with anogenital malignancies in Botswana. BMC Infect Dis. 2017 Nov 25.
Ledikwe JH, Ramabu NM, Spees LP, Barnhart S, Ntsuape C, Semo BW, Wirth KE. Early resumption of sexual activity following voluntary medical male circumcision in Botswana: A qualitative study. PLoS One. 2017 Nov 14.
Wirth KE, Semo BW, Spees LP, Ntsuape C, Barnhart S, Ledikwe JH. A prospective cohort study of safety and patient satisfaction of voluntary medical male circumcision in Botswana. PLoS One. 2017 Nov 7.
Caniglia EC, Zash R, Jacobson DL, Diseko M, Mayondi G, Lockman S, Chen J, Mmalane M, Makhema J, Hernán MA, Shapiro RL. Emulating a target trial of antiretroviral therapy regimens started before conception and risk of adverse birth outcomes. AIDS. 2017 Nov 2.
Powis KM, Souda S, Lockman S, Ajibola G, Bennett K, Leidner J, Hughes MD, Moyo S, van Widenfelt E, Jibril HB, Makhema J, Essex M, Shapiro RL. Cotrimoxazole prophylaxis was associated with enteric commensal bacterial resistance among HIV-exposed infants in a randomized controlled trial, Botswana. J Int AIDS Soc. 2017 Nov.
Chaplin B, Imade GE, Onwuamah C, Odaibo G, Audu R, Okpokwu J, Olaleye DO, Meloni S, Rawizza H, Muazu M, Musa AZ, Samuels J, Agbaji O, Ezechi O, Idigbe E, Kanki PJ. Distinct pattern of TAMs with K65R in patients failing tenofovir-based antiretroviral therapy. AIDS Res Hum Retroviruses. 2017 Oct 30.
N’Guessan KF, Anderson M, Phinius B, Moyo S, Malick A, Mbangiwa T, Choga WT, Makhema J, Marlink R, Essex M, Musonda R, Gaseitsiwe S, Blackard JT. The Impact of Human Pegivirus on CD4 Cell Count in HIV-Positive Persons in Botswana. Open Forum Infect Dis. 2017 Oct 10.
Chaudhury S, Williams PL, Mayondi GK, Leidner J, Holding P, Tepper V, Nichols S, Magetse J, Sakoi M, Moabi K, Makhema J, Mdluli C, Jibril H, Seage GR 3rd, Kammerer B, Lockman S. Neurodevelopment of HIV-Exposed and HIV-Unexposed Uninfected Children at 24 Months. Pediatrics. 2017 Oct.
Meloni ST, Chaplin B, Idoko J, Agbaji O, Akanmu S, Imade G, Okonkwo P, Murphy RL, Kanki PJ. Drug resistance patterns following pharmacy stock shortage in Nigerian Antiretroviral Treatment Program. AIDS Res Ther. 2017 Oct.
Balasubramanian R, Fowler MG, Dominguez K, Lockman S, Tookey PA, Huong NNG, Nesheim S, Hughes MD, Lallemant M, Tosswill J, Shaffer N, Sherman G, Palumbo P, Shapiro DE. Time to first positive HIV-1 DNA PCR may differ with antiretroviral regimen in infants infected with non-B subtype HIV-1. AIDS. 2017 Sep 18.
Ryan K, Anderson M, Gyurova I, Ambroggio L, Moyo S, Sebunya T, Makhema J, Marlink R, Essex M, Musonda R, Gaseitsiwe S, Blackard JT. High Rates of Occult Hepatitis B Virus Infection in HIV-Positive Individuals Initiating Antiretroviral Therapy in Botswana. Open Forum Infect Dis. 2017 Sep 13.
Zash R, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Petlo C, Lockman S, Makhema J, Shapiro RL. Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy. JAMA Pediatr. 2017 Aug 7.
Campa A, Baum MK, Bussmann H, Martinez SS, Farahani M, van Widenfelt E, Moyo S, Makhema J, Essex M, Marlink R. The effect of micronutrient supplementation on active TB incidence early in HIV infection in Botswana. Nutr Diet Suppl. 2017 July 14.
Mosepele M, Hemphill LC, Moloi W, Moyo S, Nkele I, Makhema J, Bennett K, Triant VA, Lockman S. Pre-clinical carotid atherosclerosis and sCD163 among virally suppressed HIV patients in Botswana compared with uninfected controls. PLoS One. 2017 Jun 29.
Ratmann O, Wymant C, Colijn C, Danaviah S, Essex M, Frost SDW, Gall A, Gaiseitsiwe S, Grabowski M, Gray R, Guindon S, von Haeseler A, Kaleebu P, Kendall M, Kozlov A, Manasa J, Minh BQ, Moyo S, Novitsky V, Nsubuga R, Pillay S, Quinn TC, Serwadda D, Ssemwanga D, Stamatakis A, Trifinopoulos J, Wawer M, Leigh Brown A, de Oliveira T, Kellam P, Pillay D, Fraser C. HIV-1 full-genome phylogenetics of generalized epidemics in sub-Saharan Africa: impact of missing nucleotide characters in next-generation sequences. AIDS Res Hum Retroviruses. 2017 May 25.
Essex M. The end of AIDS? Lancet Public Health. 2017 May.
Lockman S, Hughes M, Powis K, Ajibola G, Bennett K, Moyo S, van Widenfelt E, Leidner J, McIntosh K, Mazhani L, Makhema J, Essex M, Shapiro R. Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial. Lancet Glob Health. 2017 May.
Ibrahim M, Moyo S, Mohammed T, Mupfumi L, Gaseitsiwe S, Maswabi K, Ajibola G, Gelman R, Batlang O, Sakoi M, Auletta-Young C, Makhema J, Lockman S, Shapiro RL. High Sensitivity and Specificity of the Cepheid Xpert® HIV-1 Qualitative Point-of-Care Test among Newborns in Botswana. J Acquir Immune Defic Syndr. 2017 Mar 24.
Ajibola G, Zash R, Shapiro RL, Batlang O, Botebele K, Bennett K, Chilisa F, Widenfelt EV, Makhema J, Lockman S, Holmes LB, Powis KM. Detecting congenital malformations – Lessons learned from the Mpepu study, Botswana. PLoS One. 2017 Mar 24.
Agaba PA, Meloni ST, Sule HM, Agaba EI, Idoko JA, Kanki PJ. Sexual dysfunction and its determinants among women infected with HIV. Int J Gynaecol Obstet. 2017 Mar 8.
Mosepele M, Hemphill LC, Palai T, Nkele I, Bennett K, Lockman S, Triant VA. Cardiovascular disease risk prediction by the American College of Cardiology (ACC)/American Heart Association (AHA) Atherosclerotic Cardiovascular Disease (ASCVD) risk score among HIV-infected patients in sub-Saharan Africa. PLoS One. 2017 Feb 24.
Tchetgen Tchetgen EJ, Wirth KE. A general instrumental variable framework for regression analysis with outcome missing not at random. Biometrics. 2017 Feb 23.
Moyo S, Wilkinson E, Vandormael A, Wang R, Weng J, Kotokwe KP, Gaseitsiwe S, Musonda R, Makhema J, Essex M, Engelbrecht S, de Oliveira T, Novitsky V. Pairwise diversity and tMRCA as potential markers for HIV infection recency. Medicine (Baltimore). 2017 Feb.
Xie W, Agniel D, Shevchenko A, Malov SV, Svitin A, Cherkasov N, Baum MK, Campa A, Gaseitsiwe S, Bussmann H, Makhema J, Marlink RG, Novitsky V, Lee TH, Cai T, O’Brien SJ, Essex M. Genome-Wide Analyses Reveal Gene Influence on HIV Disease Progression and HIV-1C Acquisition in Southern Africa. AIDS Res Hum Retroviruses. 2017 Jan 28.
Zash RM, Souda S, Leidner J, Binda K, Hick C, Powis K, Makhema J, Mmalane M, Essex M, Lockman S, Shapiro RL. High Proportion of Deaths Attributable to HIV Among Postpartum Women in Botswana Despite Widespread Uptake of Antiretroviral Therapy. AIDS Patient Care STDS. 2017 Jan.
Moyo S, Kotokwe KP, Mohammed T, Boleo C, Mupfumi L, Chishala S, Tsalaile L, Bussmann H, Gaseitsiwe S, Musonda R, Makhema J, Baum M, Marlink R, Engelbrecht S, Essex M, Novitsky V. Short Communication: Low False Recent Rate of Limiting Antigen-Avidity Assay Combined with HIV-1 RNA Data in Botswana. AIDS Res Hum Retroviruses. 2017 Jan
Powis KM, Slogrove AL, Mofenson L. Protecting the health of our AIDS-free generation: beyond prevention of mother-to-child HIV transmission. AIDS. 2017 Jan 14.
Novitsky V, Moyo S, Wang R, Gaseitsiwe S, Essex M. Deciphering Multiplicity of HIV-1C Infection: Transmission of Closely Related Multiple Viral Lineages. PLoS One. 2016 Nov 28
Meloni ST, Chang CA, Eisen G, Jolayemi T, Banigbe B, Okonkwo PI, Kanki PJ. Long-Term Outcomes on Antiretroviral Therapy in a Large Scale-Up Program in Nigeria. PLoS One. 2016 Oct 20
Moyo S, Mohammed T, Wirth KE, Prague M, Bennett K, Holme MP, Mupfumi L, Sebogodi P, Moraka NO, Boleo C, Maphorisa CN, Seraise B, Gaseitsiwe S, Musonda RM, van Widenfelt E, Powis KM, Gaolathe T, Tchetgen Tchetgen EJ, Makhema JM, Essex M, Lockman S, Novitsky V. Point-of-care Cepheid Xpert HIV-1 Viral Load Test in Rural African Communities is Feasible and Reliable. J Clin Microbiol. 2016 Oct 12
Sudfeld CR, Lei Q, Chinyanga Y, Tumbare E, Khan N, Dapaah-Siakwan F, Sebaka A, Sibiya J, van Widenfelt E, Shapiro RL, Makhema J, Fawzi WW, Powis KM. Linear Growth Faltering Among HIV-Exposed Uninfected Children. J Acquir Immune Defic Syndr. 2016 Oct 1
Currier JS, Lockman S. Making waves: safety and efficacy of ART in women. Lancet HIV. 2016 Sep
Dryden-Peterson S, Bvochora-Nsingo M, Suneja G, Efstathiou JA, Grover S, Chiyapo S, Ramogola-Masire D, Kebabonye-Pusoentsi M, Clayman R, Mapes AC, Tapela N, Asmelash A, Medhin H, Viswanathan AN, Russell AH, Lin LL, Kayembe MK, Mmalane M, Randall TC, Chabner B, Lockman S. HIV Infection and Survival Among Women With Cervical Cancer. J Clin Oncol. 2016 Aug 29
Moyo S, Vandormael A, Wilkinson E, Engelbrecht S, Gaseitsiwe S, Kotokwe KP, Musonda R, Tanser F, Essex M, Novitsky V, de Oliveira T. Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana. PLoS One. 2016 Aug 23
Anderson M, Gaseitsiwe S, Moyo S, Thami KP, Mohammed T, Setlhare D, Sebunya TK, Powell EA, Makhema J, Blackard JT, Marlink R, Essex M, Musonda RM. Slow CD4+ T-Cell Recovery in Human Immunodeficiency Virus/Hepatitis B Virus-Coinfected Patients Initiating Truvada-Based Combination Antiretroviral Therapy in Botswana. Open Forum Infect Dis. 2016 Aug 16
Eshleman SH, Hudelson SE, Redd AD, Swanstrom R, Ou SS, Zhang XC, Ping LH, Piwowar-Manning E, Porcella SF, Sievers MF, Martens CA, Bruno D, Dukhovlinova E, McCauley M, Gamble T, Fogel JM, Sabin D, Quinn TC, Gunde L, Maliwichi M, Nhando N, Akelo V, Moyo S, Panchia R, Kumarasamy N, Chotirosniramit N, Gonçalves de Melo M, Pilotto J, Grinsztejn B, Mayer K, Chen YQ, Hughes JP, Cohen MS. Treatment as Prevention: Characterization of partner infections in the HIV Prevention Trials Network 052 trial. J Acquir Immune Defic Syndr. 2016 Aug 16
Farahani M, Price N, El-Halabi S, Mlaudzi N, Keapoletswe K, Lebelonyane R, Fetogang EB, Chebani T, Kebaabetswe P, Masupe T, Gabaake K, Auld AF, Nkomazana O, Marlink R. Impact of Health System Inputs on Health Outcome: A Multilevel Longitudinal Analysis of Botswana National Antiretroviral Program (2002-2013). PLoS One. 2016 Aug 4
Moyo S, Kotokwe KP, Mohammed T, Boleo C, Mupfumi L, Chishala S, Tsalaile L, Bussmann H, Gaseitsiwe S, Musonda R, Makhema J, Baum MK, Marlink RG, Engelbrecht S, Essex M, Novitsky V. Low False Recent Rate of Limiting Antigen-Avidity Assay Combined with HIV-1 RNA Data in Botswana. AIDS Res Hum Retroviruses. 2016 Aug 1
Zash R, Souda S, Leidner J, Ribaudo H, Binda K, Moyo S, Powis KM, Petlo C, Mmalane M, Makhema J, Essex M, Lockman S, Shapiro R. HIV-exposed children account for more than half of 24-month mortality in Botswana. BMC Pediatr. 2016 Jul 21
Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Kumwenda J, Grinsztejn B, Pilotto JH, Godbole SV, Chariyalertsak S, Santos BR, Mayer KH, Hoffman IF, Eshleman SH, Piwowar-Manning E, Cottle L, Zhang XC, Makhema J, Mills LA, Panchia R, Faesen S, Eron J, Gallant J, Havlir D, Swindells S, Elharrar V, Burns D, Taha TE, Nielsen-Saines K, Celentano DD, Essex M, Hudelson SE, Redd AD, Fleming TR; HPTN 052 Study Team. Antiretroviral Therapy for the Prevention of HIV-1 Transmission. N Engl J Med. 2016 Jul 18
Rossenkhan R, MacLeod IJ, Brumme ZL, Magaret C, Sebunya TK, Musonda R, Gashe BA, Novitsky V, Edlefsen P, Essex M. Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection. AIDS Res Hum Retroviruses. 2016 Jun 28
Lin N, Gonzalez OA, Registre L, Becerril C, Etemad B, Lu H, Wu X, Lockman S, Essex M, Moyo S, Kuritzkes DR, Sagar M. Humoral Immune Pressure Selects for HIV-1 CXC-chemokine Receptor 4-using Variants. EBioMedicine. 2016 Jun
Ogwu A, Moyo S, Powis K, Asmelash A, Lockman S, Moffat C, Leidner J, Makhema J, Essex M, Shapiro R. Predictors of Early Breastfeeding Cessation among HIV-infected women in Botswana. Trop Med Int Health. 2016 May 25
Perry ME, Kalenga K, Francois Watkins L, Mukaya JE, Powis KM, Bennett K, Mmalane M, Makhema J, Shapiro RL. HIV-related mortality at a district hospital in Botswana. Int J STD AIDS. 2016 May 9
Sudfeld CR, Lei Q, Chinyanga Y, Tumbare E, Khan N, Dapaah-Siakwan F, Sebaka A, Sibiya J, van Widenfelt E, Shapiro RL, Makhema J, Fawzi WW, Powis KM. Linear Growth Faltering Among HIV-Exposed Uninfected Children. J Acquir Immune Defic Syndr. 2016 Apr 21
Borges ÁH, Lundh A, Tendal B, Bartlett JA, Clumeck N, Costagliola D, Daar ES, Echeverría P, Gisslén M, Huedo-Medina TB, Hughes MD, Huppler Hullsiek K, Khabo P, Komati S, Kumar P, Lockman S, MacArthur RD, Maggiolo F, Matteelli A, Miro JM, Oka S, Petoumenos K, Puls RL, Riddler SA, Sax PE, Sierra-Madero J, Torti C, Lundgren JD. Nonnucleoside Reverse-transcriptase Inhibitor- vs Ritonavir-boosted Protease Inhibitor-based Regimens for Initial Treatment of HIV Infection: A Systematic Review and Metaanalysis of Randomized Trials. Clin Infect Dis. 2016 Apr 18
Martinez SS, Campa A, Bussmann H, Moyo S, Makhema J, Huffman FG, Williams OD, Essex M, Marlink R, Baum MK. Effect of BMI and fat mass on HIV disease progression in HIV-infected, antiretroviral treatment-naïve adults in Botswana. Br J Nutr. 2016 Apr 18
Brown CA, Suneja G, Tapela N, Mapes A, Pusoentsi M, Mmalane M, Hodgeman R, Boyer M, Musimar Z, Ramogola-Masire D, Grover S, Nsingo-Bvochora M, Kayembe M, Efstathiou J, Lockman S, Dryden-Peterson S. Predictors of Timely Access of Oncology Services and Advanced-Stage Cancer in an HIV-Endemic Setting. Oncologist. 2016 Apr 6
Zash R, Souda S, Chen JY, Binda K, Dryden-Peterson S, Lockman S, Mmalane M, Makhema J, Essex M, Shapiro R. Reassuring Birth Outcomes With Tenofovir/Emtricitabine/Efavirenz Used for Prevention of Mother-to-Child Transmission of HIV in Botswana. J Acquir Immune Defic Syndr. 2016 Apr 1
Tendani Gaolathe, MD, Kathleen E Wirth, ScD, Molly Pretorius Holme, MS, Joseph Makhema, FRCP, Sikhulile Moyo, MSc,Unoda Chakalisa, MD, Etienne Kadima Yankinda, MPH, Quanhong Lei, PhD, Mompati Mmalane, MSc, Vlad Novitsky, PhD,Lillian Okui, MPH, Erik van Widenfelt, BA, Kathleen M Powis, MD, Nealia Khan, MPH, Kara Bennett, MS, Hermann Bussmann, MD, Scott Dryden-Peterson, MD, Refeletswe Lebelonyane, MPH, Shenaaz el-Halabi, MPH, Lisa A Mills, MD,Tafireyi Marukutira, MD, Rui Wang, PhD, Prof Eric J Tchetgen Tchetgen, PhD, Prof Victor DeGruttola, DSc, Prof M Essex, PhD, Shahin Lockman, MD, Botswana Combination Prevention Project study team. Botswana’s progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey. The Lancet HIV. Published Online: 23 March 2016
Ebonyi AO, Oguche S, Ejeliogu EU, Agbaji OO, Shehu NY, Abah IO, Sagay AS, Ugoagwu PO, Okonkwo PI, Idoko JA, Kanki PJ. Prevalence of and risk factors for pulmonary tuberculosis among newly diagnosed HIV-1 infected Nigerian children. Germs. 2016 Mar 1
Rowley CF, MacLeod IJ, Maruapula D, Lekoko B, Gaseitsiwe S, Mine M, Essex M. Sharp increase in rates of HIV-transmitted drug resistance at antenatal clinics in Botswana demonstrates the need for routine surveillance. J Antimicrob Chemother. 2016 Feb 29
Ahmed S, Bärnighausen T, Daniels N, Marlink R, Roberts MJ. How providers influence the implementation of provider-initiated HIV testing and counseling in Botswana: a qualitative study. Implement Sci. 2016 Feb 11
Farahani M, Mulinder H, Farahani A, Marlink R. Prevalence and distribution of non-AIDS causes of death among HIV-infected individuals receiving antiretroviral therapy: a systematic review and meta-analysis. Int J STD AIDS. 2016 Feb 10
Farahani M, Novitsky V, Wang R, Bussmann H, Moyo S, Musonda RM, Moeti T, Makhema JM, Essex M, Marlink R. Prognostic Value of HIV-1 RNA on CD4 Trajectories and Disease Progression Among Antiretroviral-Naive HIV-Infected Adults in Botswana: A Joint Modeling Analysis. AIDS Res Hum Retroviruses. 2016 Jun
Mayondi GK, Wirth K, Morroni C, Moyo S, Ajibola G, Diseko M, Sakoi M, Magetse JD, Moabi K, Leidner J, Makhema J, Kammerer B, Lockman S. Unintended pregnancy, contraceptive use, and childbearing desires among HIV-infected and HIV-uninfected women in Botswana: across-sectional study. BMC Public Health. 2016 Jan
Kathleen E. Wirth Bazghina-werq Semo, Conrad Ntsuape, Nankie M. Ramabu, Boyce Otlhomile, Rebeca M. Plank, Scott Barnhart Jenny H. Ledikwe. Triggering the decision to undergo medical male circumcision: a qualitative study of adult men in Botswana. AIDS Care. 2016 Jan
Powis KM, Smeaton L, Hughes MD, Tumbare EA, Souda S, Jao J, Wirth KE, Makhema J, Lockman S, Fawzi W, Essex M, Shapiro RL. In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana. AIDS. 2016 Jan
Novitsky V, Kühnert D, Moyo S, Widenfelt E, Okui L, Essex M. Phylodynamic analysis of HIV sub-epidemics in Mochudi, Botswana. Epidemics. 2015 Dec
Wirth KE, Agniel D, Barr CD, Austin MD, DeGruttola V. A composite likelihood approach for estimating HIV prevalence in the presence of spatial variation. Stat Med. 2015 Dec 10
Kelly MS, Wirth KE, Steenhoff AP, Cunningham CK, Arscott-Mills T, Boiditswe SC, Patel MZ, Shah SS, Finalle R, Makone I, Feemster KA. Treatment Failures and Excess Mortality Among HIV-Exposed, Uninfected Children With Pneumonia. J Pediatric Infect Dis Soc. 2015 Dec 4
Farahani M, Price N, El-Halabi S, Mlaudzi N, Keapoletswe K, Lebelonyane R, Fetogang EB, Chebani T, Kebaabetswe P, Masupe T, Gabaake K, Auld A, Nkomazana O, Marlink R. Trends and determinants of survival for over 200 000 patients on antiretroviral treatment in the Botswana National Program: 2002-2013. AIDS. 2015 Dec 3
Auld AF, Shiraishi RW, Mbofana F, Couto A, Fetogang EB, El-Halabi S, Lebelonyane R, Pilatwe PT, Hamunime N, Okello V, Mutasa-Apollo T, Mugurungi O, Murungu J, Dzangare J, Kwesigabo G, Wabwire-Mangen F, Mulenga M, Hachizovu S, Ettiegne-Traore V, Mohamed F; MSAE, Bashorun A, Nhan do T, Hai NH, Quang TH, Van Onacker JD, Francois K, Robin EG, Desforges G, Farahani M, Kamiru H, Nuwagaba-Biribonwoha H, Ehrenkranz P, Denison JA, Koole O, Tsui S, Torpey K, Mukadi YD, van Praag E, Menten J, Mastro TD, Hamilton CD, Abiri OO, Griswold M, Pierre E, Xavier C, Alfredo C, Jobarteh K, Letebele M, Agolory S, Baughman AL, Mutandi G, Preko P, Ryan C, Ao T, Gonese E, Herman-Roloff A, Ekra KA, Kouakou JS, Odafe S, Onotu D, Dalhatu I, Debem HH, Nguyen DB, Yen le N, Abdul-Quader AS, Pelletier V, Williams SG, Behel S, Bicego G, Swaminathan M, Dokubo EK, Adjorlolo-Johnson G, Marlink R, Lowrance D, Spira T, Colebunders R, Bangsberg D, Zee A, Kaplan J, Ellerbrock TV. Lower Levels of Antiretroviral Therapy Enrollment Among Men with HIV Compared with Women – 12 Countries, 2002-2013. MMWR Morb Mortal Wkly Rep. 2015 Nov 27
Scarsi KK, Eisen G, Darin KM, Meloni ST, Rawizza HE, Tchetgen Tchetgen EJ, Agbaji O, Onwujekwe DI, Gashau W, Nkado R, Okonkwo P, Murphy RL, Kanki PJ; Harvard/APIN PEPFAR Team. Superior effectiveness of zidovudine compared to tenofovir when combined with nevirapine-based antiretroviral therapy in a large Nigerian Cohort. Clin Infect Dis. 2015 Nov 10
Grover S, Raesima M, Bvochora-Nsingo M, Chiyapo SP, Balang D, Tapela N, Balogun O, Kayembe MK, Russell AH, Monare B, Tanyala S, Bhat J, Thipe K, Nchunga M, Mayisela S, Kizito B, Ho-Foster A, Gaolebale BE, Gaolebale PA, Efstathiou JA, Dryden-Peterson S, Zetola N, Hahn SM, Robertson ES, Lin LL, Morroni C, Ramogola-Masire D. Cervical Cancer in Botswana: Current State and Future Steps for Screening and Treatment Programs. Front Oncol. 2015 Nov 3
Moyo S, Wilkinson E, Novitsky V, Vandormael A, Gaseitsiwe S, Essex M, Engelbrecht S, de Oliveira T. Identifying Recent HIV Infections: From Serological Assays to Genomics. Viruses. 2015 Oct 23
Farahani M, Price N, El-Halabi S, Mlaudzi N, Keapoletswe K, Lebelonyane R, Fetogang EB, Chebani T, Kebaabetswe P, Masupe T, Gabaake K, Auld A, Nkomazana O, Marlink R. Variation in attrition at sub-national level: Review of the Botswana National HIV/AIDS Treatment (Masa) program data (2002-2013). Trop Med Int Health. 2015 Oct 20
Chang CA, Meloni ST, Eisen G, Chaplin B, Akande P, Okonkwo P, Rawizza HE, Tchetgen Tchetgen E, Kanki PJ. Tuberculosis Incidence and Risk Factors Among Human Immunodeficiency Virus (HIV)-Infected Adults Receiving Antiretroviral Therapy in a Large HIV Program in Nigeria. Open Forum Infect Dis. 2015 Oct 17
Wu JW, Patterson-Lomba O, Novitsky V, Pagano M. A Generalized Entropy Measure of Within-Host Viral Diversity for Identifying Recent HIV-1 Infections. Medicine (Baltimore). 2015 Oct
Iketleng T, Moyo S, Gaseitsiwe S, Nyombi BM, Mitchell R, Makhema J, Baum MK, Marlink RG, Essex M, Musonda R. Plasma Cytokine Levels in Chronic Asymptomatic HIV-1 Subtype C Infection as an Indicator of Disease Progression in Botswana: A Retrospective Case Control Study. AIDS Res Hum Retroviruses. 2015 Sep 28
Abah IO, Akanbi M, Abah ME, Finangwai AI, Dady CW, Falang KD, Ebonyi AO, Okopi JA, Agbaji OO, Sagay AS, Okonkwo P, Idoko JA, Kanki PJ. Incidence and predictors of adverse drug events in an African cohort of HIV-infected adults treated with efavirenz. Germs. 2015 Sep 1
Zash R, Souda S, Chen JY, Binda K, Dryden-Peterson S, Lockman S, Mmalane M, Makhema J, Essex M, Shapiro R. Reassuring Birth Outcomes with Tenofovir/Emtricitabine/Efavirenz used for Prevention of Mother to Child Transmission of HIV in Botswana. J Acquir Immune Defic Syndr. 2015 Sep 12
Schaan MM, Taylor M, Gungqisa N, Marlink R. Personal views about womanhood amongst women living with HIV in Botswana. Cult Health Sex. 2015 Aug 25
Liu SH, Erion G, Novitsky V, De Gruttola V. Viral Genetic Linkage Analysis in the Presence of Missing Data. PLoS One. 2015 Aug 24
Novitsky V, Zahralban-Steele M, McLane MF, Moyo S, van Widenfelt E, Gaseitsiwe S, Makhema J, Essex M. Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering. J Clin Microbiol. 2015 Aug
Anderson M, Gaseitsiwe S, Moyo S, Wessels MJ, Mohammed T, Sebunya TK, Powell EA, Makhema J, Blackard JT, Marlink R, Essex M, Musonda RM. Molecular characterisation of hepatitis B virus in HIV-1 subtype C infected patients in Botswana. BMC Infect Dis. 2015 Aug 13
Dryden-Peterson S, Medhin H, Kebabonye-Pusoentsi M, Seage GR 3rd, Suneja G, Kayembe MK, Mmalane M, Rebbeck T, Rider JR, Essex M, Lockman S. Cancer Incidence following Expansion of HIV Treatment in Botswana. PLoS One. 2015 Aug 12
De Neve JW, Fink G, Subramanian SV, Moyo S, Bor J. Length of secondary schooling and risk of HIV infection in Botswana: evidence from a natural experiment. Lancet Glob Health. 2015 Aug 3
Matthews PC, Beloukas A, Malik A, Carlson JM, Jooste P, Ogwu A, Shapiro R, Riddell L, Chen F, Luzzi G, Jaggernath M, Jesuthasan G, Jeffery K, Ndung’u T, Goulder PJ, Geretti AM, Klenerman P. Prevalence and Characteristics of Hepatitis B Virus (HBV) Coinfection among HIV-Positive Women in South Africa and Botswana. PLoS One. 2015 Jul 28
Adland E, Paioni P, Thobakgale C, Laker L, Mori L, Muenchhoff M, Csala A, Clapson M, Flynn J, Novelli V, Hurst J, Naidoo V, Shapiro R, Huang KH, Frater J, Prendergast A, Prado JG, Ndung’u T, Walker BD, Carrington M, Jooste P, Goulder PJ. Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection. PLoS Pathog. 2015 Jun 15
Zash RM, Shapiro RL, Leidner J, Wester C, McAdam AJ, Hodinka RL, Thior I, Moffat C, Makhema J, McIntosh K, Essex M, Lockman S. The aetiology of diarrhoea, pneumonia and respiratory colonization of HIV-exposed infants randomized to breast- or formula-feeding. Paediatr Int Child Health. 2015 Jun 8
Novitsky V, Bussmann H, Okui L, Logan A, Moyo S, van Widenfelt E, Mmalane M, Lei Q, Holme MP, Makhema J, Lockman S, Degruttola V, Essex M. Estimated age and gender profile of individuals missed by a home-based HIV testing and counselling campaign in a Botswana community. J Int AIDS Soc. 2015 May 29
Tchetgen EJ, Phiri K, Shapiro R. A Simple Regression-based Approach to Account for Survival Bias in Birth Outcomes Research. Epidemiology. 2015 May 22
Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M. Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering. AIDS Res Hum Retroviruses. 2015 May
Mackelprang RD, Scoville CW, Cohen CR, Ondondo RO, Bigham AW, Celum C, Campbell MS, Essex M, Wald A, Kiarie J, Ronald A, Gray G, Lingappa JR. Toll-like receptor gene variants and bacterial vaginosis among HIV-1 infected and uninfected African women. Genes Immun. 2015 Apr 30
Dryden-Peterson S, Bennett K, Hughes MD, Veres A, John O, Pradhananga R, Boyer M, Brown C, Sakyi B, van Widenfelt E, Keapoletswe K, Mine M, Moyo S, Asmelash A, Siedner M, Mmalane M, Shapiro RL, Lockman S. An Augmented SMS Intervention to Improve Access to Antenatal CD4 Testing and ART Initiation in HIV-Infected Pregnant Women: A Cluster Randomized Trial. PLoS One. 2015 Feb 18
Abah IO, Darin KM, Ebonyi AO, Ugoagwu P, Ojeh VB, Nasir N, Falang KD, Olaitan O, Agbaji O, Idoko J, Kanki P. Patterns and Predictors of First-Line Antiretroviral Therapy Modification in HIV-1-Infected Adults in a Large Urban Outpatient Cohort in Nigeria. J Int Assoc Provid AIDS Care. 2015 Jan 7
Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M. Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering. AIDS Res Hum Retroviruses. 2015 Jan 6
Dryden-Peterson S, Lockman S, Zash R, Lei Q, Chen JY, Souda S, Petlo C, Dintwa E, Lebelonyane R, Mmalane M, Shapiro RL. Initial Programmatic Implementation of WHO Option B in Botswana Associated with Increased Projected MTCT. J Acquir Immune Defic Syndr. 2014 Dec 11
Payne R, Muenchhoff M, Mann J, Roberts HE, Matthews P, Adland E, Hempenstall A, Huang KH, Brockman M, Brumme Z, Sinclair M, Miura T, Frater J, Essex M, Shapiro R, Walker BD, Ndung’u T, McLean AR, Carlson JM, Goulder PJ. Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence. Proc Natl Acad Sci. 2014 Dec 1
Chaplin B, Meloni S, Eisen G, Jolayemi T, Banigbe B, Adeola J, Wen C, Reyes Nieva H, Chang C, Okonkwo P, Kanki P. Scale-up of networked HIV treatment in Nigeria: Creation of an integrated electronic medical records system. Int J Med Inform. 2014 Sep 30
Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M. Impact of Sampling Density on the Extent of HIV Clustering. AIDS Res Hum Retroviruses. 2014 Oct 2
Liu KC, Farahani M, Mashamba T, Mawela M, Joseph J, Van Schaik N, Honey E, Gill M, Jassat W, Stringer EM, Chintu N, Marlink RG. Pregnancy outcomes and birth defects from an antiretroviral drug safety study of women in South Africa and Zambia. AIDS. 2014 Aug 11
Powis K, Lockman S, Smeaton L, Hughes MD, Fawzi W, Ogwu A, Moyo S, van Widenfelt E, von Oettingen J, Makhema J, Essex M, Shapiro RL. Vitamin D Insufficiency in HIV-Infected Pregnant Women Receiving Antiretroviral Therapy is not associated with Morbidity, Mortality or Growth Impairment in Their Uninfected Infants in Botswana. Pediatr Infect Dis J. 2014 Jul 16
Asmelash A, Zheng Y, Kaloustian KW, Shaffer D, Sawe F, Ogwu A, Salata R, Currier J, Hughes MD, Lockman S. Predictors of suboptimal CD4 response among women achieving virologic suppression in a randomized antiretroviral treatment Trial, Africa. BMC Infect Dis. 2014 Jun 17
Kanki PJ, Rowland-Jones S. The protective effect of HIV-2 infection: implications for understanding HIV-1 immunity. AIDS. 2014 Apr 24
Shao ER, Kifaro EG, Chilumba IB, Nyombi BM, Moyo S, Gaseitsiwe S, Musonda R, Johannessen A, Kibiki G, Essex M. HIV-1 drug mutations in children from northern Tanzania. J Antimicrob Chemother. 2014 Apr 11
Auld AF, Tuho MZ, Ekra KA, Kouakou J, Shiraishi RW, Adjorlolo-Johnson G, Marlink R, Ellerbrock TV. Tuberculosis in human immunodeficiency virus-infected children starting antiretroviral therapy in Côte d’Ivoire. Int J Tuberc Lung Dis. 2014 Apr.
Russell ES, Mohammed T, Smeaton L, Jorowe B, Macleod IJ, Hoffman RM, Currier JS, Moyo S, Essex M, Lockman S. Immune activation markers in peripartum women in botswana: association with feeding strategy and maternal morbidity. PLoS One. 2014 Mar 21
Wang R, Goyal R, Lei Q, Essex M, De Gruttola V. Sample size considerations in the design of cluster randomized trials of combination HIV prevention. Clin Trials. 2014 Mar 20
Plank RM, Wirth KE, Ndubuka NO, Abdullahi R, Nkgau M, Lesetedi C, Powis KM, Mmalane M, Makhema J, Shapiro R, Lockman S. Single-Arm Evaluation of the AccuCirc Device for Early Infant Male Circumcision in Botswana. J Acquir Immune Defic Syndr. 2014 Mar 3
Grinsztejn B, Hosseinipour MC, Ribaudo HJ, Swindells S, Eron J, Chen YQ, Wang L, Ou SS, Anderson M, McCauley M, Gamble T, Kumarasamy N, Hakim JG, Kumwenda J, Pilotto JH, Godbole SV, Chariyalertsak S, de Melo MG, Mayer KH, Eshleman SH, Piwowar-Manning E, Makhema J, Mills LA, Panchia R, Sanne I, Gallant J, Hoffman I, Taha TE, Nielsen-Saines K, Celentano D, Essex M, Havlir D, Cohen MS; the HPTN 052-ACTG Study Team. Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled trial. Lancet Infect Dis. 2014 Mar 3
Kahle EM, Kashuba A, Baeten JM, Fife KH, Celum C, Mujugira A, Essex M, De Bruyn G, Wald A, Donnell D, John-Stewart G, Delany-Moretlwe S, Mugo NR, Farquhar C, Lingappa JR; Partners in Prevention HSVHIV Transmission Study Team. Unreported antiretroviral use by HIV-1-infected participants enrolling in a prospective research study. J Acquir Immune Defic Syndr. 2014 Feb 1
Farahani M., Vable A., Lebelonyane R., Seipone K., Anderson M., Avalos A., Chadborn T., Tilahun H., Roumis Themba Moeti D., Musuka G., Busang L., Gaolathe T., C S Malefho K., Marlink R.Outcomes of the Botswana national HIV/AIDS treatment programme from 2002 to 2010: a longitudinal analysis. The Lancet Global Health. January 2014
Shaffer D, Hughes MD, Sawe F, Bao Y, Moses A, Hogg E, Lockman S, Currier J. Cardiovascular Disease Risk Factors in HIV-Infected Women Following Initiation of Lopinavir/ritonavir- and Nevirapine-based Antiretroviral Therapy in Sub-Saharan Africa: A5208 (“OCTANE”). J Acquir Immune Defic Syndr. 2014 Feb 20
Mwafongo A, Nkanaunena K, Zheng Y, Hogg E, Samaneka W, Mulenga L, Siika A, Currier J, Lockman S, Hughes MD, Hosseinipour M; for the AIDS Clinical Trial Group (ACTG) A5208 Team.Renal events among women treated with tenofovir/emtricitabine in combination with either lopinavir/ritonavir or nevirapine: analysis from the AIDS Clinical Trial Group A5208 trial. AIDS 2014 Jan 18
Boltz VF, Bao Y, Lockman S, Halvas EK, Kearney MF, McIntyre JA, Schooley RT, Hughes MD, Coffin JM, Mellors JW; for the OCTANE/A5208 Team. Low-Frequency Nevirapine (NVP)-Resistant HIV-1 Variants Are Not Associated With Failure of Antiretroviral Therapy in Women Without Prior Exposure to Single-Dose NVP. J Infect Dis. 2014 Jan 16
Zash RM, Ajose-Popoola O, Stordal K, Souda S, Ogwu A, Dryden-Peterson S, Powis K, Lockman S, Makhema J, Essex M, Shapiro RL. Risk factors for mortality among human immunodeficiency virus-exposed and unexposed infants admitted to a neonatal intensive care unit in Botswana.
J Paediatr Child Health. 2013 Dec 23
Novitsky V, Bussmann H, Logan A, Moyo S, van Widenfelt E, Okui L, Mmalane M, Baca J, Buck L, Phillips E, Tim D, McLane MF, Lei Q, Wang R, Makhema J, Lockman S, Degruttola V, Essex M.Phylogenetic Relatedness of Circulating HIV-1C Variants in Mochudi, Botswana. PLoS One. 2013 Dec 11
Baum MK, Campa A, Lai S, Sales Martinez S, Tsalaile L, Burns P, Farahani M, Li Y, van Widenfelt E, Page JB, Bussmann H, Fawzi WW, Moyo S, Makhema J, Thior I, Essex M, Marlink R. Effect of micronutrient supplementation on disease progression in asymptomatic, antiretroviral-naive, HIV-infected adults in Botswana: a randomized clinical trial. JAMA. 2013 Nov 27
Pramanik Sollerkvist L, Gaseitsiwe S, Mine M, Sebetso G, Mphoyakgosi T, Diphoko T, Essex M, Ehrnst A. Increased CXCR4 use of HIV-1 subtype C identified by population sequencing in patients failing antiretroviral treatment compared with treatment-naïve patients in Botswana. AIDS Res Hum Retroviruses. 2013 Nov 8
Imade GE, Sagay AS, Chaplin B, Chebu PR, Musa J, Okpokwu J, Hamel D, Pam IC, Agbaji O, Samuels J, Meloni S, Sankalé JL, Okonkwo P, Kanki PJ.Transmitted HIV drug resistance in antiretroviral-naïve pregnant women in north central Nigeria. AIDS Res Hum Retroviruses. 2013 Oct 28
Dryden-Peterson S, Jayeoba O, Hughes MD, Jibril H, McIntosh K, Modise TA, Asmelash A, Powis KM, Essex M, Shapiro RL, Lockman S. Cotrimoxazole Prophylaxis and Risk of Severe Anemia or Severe Neutropenia in HAART-Exposed, HIV-Uninfected Infants. PLoS One. 2013 Sep 23
Rawizza HE, Chaplin B, Meloni ST, Darin KM, Olaitan O, Scarsi KK, Onwuamah CK, Audu RA, Chebu PR, Imade GE, Okonkwo P, Kanki PJ. Accumulation of Protease Mutations among Patients Failing Second-Line Antiretroviral Therapy and Response to Salvage Therapy in Niger PLoS One. 2013 Sep 17
Moyo S, Lecuyer T, Wang R, Gaseitsiwe S, Weng J, Musonda R, Bussmann H, Mine M, Engelbrecht S, Makhema J, Marlink RG, Baum MK, Novitsky V, Essex M. Evaluation of the False Recent Classification Rates of Multi-Assay Algorithms in Estimating HIV-1 Subtype C Incidence.AIDS Res Hum Retroviruses. 2013 Aug 12
Kiwelu IE, Novitsky V, Margolin L, Baca J, Manongi R, Sam N, Shao J, McLane MF, Kapiga SH, Essex M. Frequent Intra-Subtype Recombination among HIV-1 Circulating in Tanzania. PLoS One. 2013 Aug 5
Musa J, Taiwo B, Achenbach C, Olugbenga S, Berzins B, Sagay AS, Idoko JA, Kanki PJ, Murphy RL. High-risk human papillomavirus among HIV-infected women with normal cervical cytology: a pilot study in Jos, Nigeria. Arch Gynecol Obstet. 2013 May 23
McDonald B, Moyo S, Gabaitiri L, Gaseitsiwe S, Bussmann H, Koethe JR, Musonda R, Makhema J, Novitsky V, Marlink RG, Wester CW, Essex M. Persistently Elevated Serum Interleukin-6 Predicts Mortality among Adults Receiving Combination Antiretroviral Therapy in Botswana: Results from a Clinical Trial. AIDS Res Hum Retroviruses. 2013 Apr 16
Souda S, Gaseitsiwe S, Georgette N, Powis K, Moremedi D, Iketleng T, Leidner J, Moffat C, Ogwu A, Lockman S, Moyo S, Mmalane M, Musonda R, Makhema J, Essex M, Shapiro R. No Clinically Significant Drug Resistance Mutations In HIV-1 subtype C Infected Women After Discontinuation Of NRTI-Based Or PI-Based HAART For PMTCT In Botswana. J Acquir Immune Defic Syndr. 2013 Mar 28
Wang R, Weng J, Moyo S, Pain D, Barr CD, Maruapula D, Mongwato D, Makhema J, Novitsky V, Essex M. Effect of short-course antenatal Zidovudine and single-dose Nevaripine on the BED capture enzyme immunoassay levels in HIV-1 subtype C infection. AIDS Res Hum Retroviruses. 2013 Mar 22
Ladep NG, Agaba PA, Agbaji O, Muazu A, Ugoagwu P, Imade G, Cooke G, McCormack S, Taylor-Robinson SD, Idoko J, Kanki P. Rates and impact of hepatitis on human immunodeficiency virus infection in a large African cohor. World J Gastroenterol. 2013 Mar 14
Novitsky V, Wang R, Rossenkhan R, Moyo S, Essex M. Intra-Host Evolutionary Rates in HIV-1C env and gag during Primary Infection. Infect Genet Evol. 2013 Mar 19
Rossenkhan R, Macleod IJ, Sebunya TK, Castro-Nallar E, McLane MF, Musonda R, Gashe BA, Novitsky V, Essex M. Tat exon 1 Exhibits Functional Diversity During HIV-1 Subtype C Primary Infection. J Virol. 2013 Mar 13
Dinic L, Idigbe OE, Meloni S, Rawizza H, Akande P, Eisen G, Onwujekwe D, Agbaji O, Ani A, Kanki PJ. Sputum smear concentration may misidentify acid-fast bacilli as Mycobacterium tuberculosis (Mtb) in HIV-infected patients. J Acquir Immune Defic Syndr. 2013 Feb 7
Finucane MM, Rowley CF, Paciorek CJ, Essex M, Pagano M. Estimating the prevalence of transmitted HIV drug resistance using pooled samples. Stat Methods Med Res. 2013 Feb 1
Powis KM, McElrath TF, Hughes MD, Ogwu A, Souda S, Datwyler SA, von Widenfelt E, Moyo S, Nádas M, Makhema J, Machakaire E, Lockman S, Essex M, Shapiro RL. High Viral Load and Elevated Angiogenic Markers Associated with Increased Risk of Preeclampsia among Women Initiating Highly Active Antiretroviral Therapy (HAART) in Pregnancy in the Mma Bana Study, Botswana. J Acquir Immune Defic Syndr. 2013 Jan 22
Akanbi MO, Achenbach C, Feinglass J, Taiwo B, Adamu O, Mai P, Agbaji O, Kanki PJ, Murphy RTuberculosis after One Year of Combination Antiretroviral Therapy in Nigeria. AIDS Res Hum Retroviruses. 2013 Jan 15
Plank RM, Ndubuka NO, Wirth KE, Mwambona JT, Kebaabetswe P, Bassil B, Lesetedi C, Hussein FM, Magetse J, Nkgau M, Makhema J, Mmalane M, Creek T,Powis KM, Shapiro R, Lockman S. A Randomized Trial of Mogen Clamp versus Plastibell for Neonatal Male Circumcision in Botswana. J Acquir Immune Defic Syndr. 2013 Jan 10
Mazzeo CI, Flanagan EH, Bobrow EA, Pitter CS, Marlink R. How the global call for elimination of pediatric HIV can support HIV-positive women to achieve their pregnancy intentions. Reprod Health Matters. 2012 Dec 20
Matthews PC, Koyanagi M, Kløverpris HN, Harndahl M, Stryhn A, Akahoshi T, Gatanaga H, Oka S, Juarez Molina C, Valenzuela Ponce H, Avila Rios S, Cole D,Carlson J, Payne RP, Ogwu A, Bere A, Ndung’u T, Gounder K, Chen F, Riddell L, Luzzi G, Shapiro R, Brander C, Walker B, Sewell AK, Reyes Teran G,Heckerman D, Hunter E, Buus S, Takiguchi M, Goulder PJ. Differential Clade-Specific HLA-B*3501 Association with HIV-1 Disease Outcome Is Linked to Immunogenicity of a Single Gag Epitope. J Virol. 2012 Dec
Sawe F, Lockman S. To B or Not to B? That Is the Question, for Global Mother-to-Child HIV-1 Transmission Prevention Programs. Clin Infect Dis. 2012 Nov 30
Agbaji O, Thio CL, Meloni S, Graham C, Muazu M, Nimzing L, Idoko J, Sankalé JL, Ekong E, Murphy R, Kanki P, Hawkins C. Impact of Hepatitis C Virus on HIV Response to Antiretroviral Therapy in Nigeria. J Acquir Immune Defic Syndr. 2012 Nov 28
Shapiro RL., Rossi S., Ogwu A., Moss M., Leidner J., Moffat C., Lockman S., Moyo S., Makhema J., Essex M., Capparelli E. Therapeutic levels of lopinavir in late pregnancy and abacavir passage into breast milk, in the Mma Bana Study, Botswana. Antivir Ther. 2012 Nov 26
Lin NH, Becerril C, Giguel F, Novitsky V, Moyo S, Makhema J, Essex M, Lockman S, Kuritzkes DR, Sagar M. Env sequence determinants in CXCR4-using human immunodeficiency virus type-1 subtype C. Virology. 2012 Nov 25
Kiwelu IE, Novitsky V, Margolin L, Baca J, Manongi R, Sam N, Shao J, McLane MF, Kapiga SH, Essex. HIV-1 Subtypes and Recombinants in Northern Tanzania: Distribution of Viral Quasispecies. PLoS One. 2012
Thio CL, Smeaton L, Saulynas M, Hwang H, Saravanan S, Kulkarni S, Hakim J, Nyirenda M, Iqbal HS, Lalloo UG, Mehta AS, Hollabaugh K, Campbell TB,Lockman S, Currier JS. Characterization of HIV-HBV co-infection in a multi-national HIV-infected cohort. AIDS. 2012 Oct 22
Matthews PC, Listgarten J, Carlson JM, Payne R, Huang KH, Frater J, Goedhals D, Steyn D, van Vuuren C, Paioni P, Jooste P, Ogwu A, Shapiro R, Mncube Z,Ndung’u T, Walker BD, Heckerman D, Goulder PJ. Co-Operative Additive Effects between HLA Alleles in Control of HIV-1. PLoS One. 2012
Chen JY, Ribaudo HJ, Souda S, Parekh N, Ogwu A, Lockman S, Powis K, Dryden-Peterson S, Creek T, Jimbo W, Madidimalo T, Makhema J, Essex M, Shapiro RL. Highly Active Antiretroviral Therapy and Adverse Birth Outcomes Among HIV-Infected Women in Botswana. J Infect Dis. 2012 Oct 12
Schaan MM, Taylor M, Puvimanasinghe J, Busang L, Keapoletswe K, Marlink R. Sexual and reproductive health needs of HIV-positive women in Botswana – a study of health care worker’s views. AIDS Care. 2012
Mackelprang RD, Baeten JM, Donnell D, Celum C, Farquhar C, de Bruyn G, Essex M, McElrath MJ, Nakku-Joloba E, Lingappa JR; for the Partners in Prevention HSV/HIV Transmission Study Team. Quantifying Ongoing HIV-1 Exposure in HIV-1-Serodiscordant Couples to Identify Individuals With Potential Host Resistance to HIV-1. J Infect Dis. 2012 Oct
Wester CW, Eden SK, Shepherd BE, Bussmann H, Novitsky V, Samuels DC, Hendrickson SL, Winkler CA, O’Brien SJ, Essex M, D’Aquila RT, Degruttola V, Marlink RG. Risk factors for symptomatic hyperlactatemia and lactic acidosis among combination antiretroviral therapy-treated adults in botswana: results from a clinical trial. AIDS Res Hum Retroviruses. 2012 Aug 28
Padian NS, Isbell MT, Russell ES, Essex M. The future of HIV prevention. J Acquir Immune Defic Syndr. 2012 Aug 1
Marlink R, El-Sadr W, Simao M, Katabira E. Engaging to End the Epidemic: Seven Essential Steps Toward an AIDS-Free Generation. J Acquir Immune Defic Syndr. 2012 Aug 1
MacLeod IJ, Rowley CF, Lockman S, Ogwu A, Moyo S, van Widenfelt E, Mmalane M, Makhema J, Essex M, Shapiro RL. Abacavir alters the transcription of inflammatory cytokines in virologically suppressed, HIV-infected women. J Int AIDS Soc. 2012 Jul 10
Dinic L, Akande P, Idigbe EO, Ani A, Onwujekwe D, Agbaji O, Akanbi M, Nwosu R, Adeniyi B, Wahab M, Lekuk C, Kunle-Ope C, Nwokoye N, Kanki P. Genetic determinants of drug-resistant tuberculosis among HIV-infected patients in Nigeria. J Clin Microbiol. 2012 Sep
Rossenkhan, R., Novitsky, V., Sebunya, T.K., Leidner, J., Hagan, J.E., Moyo, S., Smeaton, L., Lockman, S., Musonda, R., Ndung’u, T., Gaseitsiwe, S., Thior, I., Mmalane, M., Makhema, J., Essex, M., Shapiro, R. Infant Feeding Practices were not Associated with Breast Milk HIV-1 RNA Levels in a Randomized Clinical Trial in Botswana. AIDS Behav. 2012 Jul
Lockman S, Hughes M, Sawe F, Zheng Y, McIntyre J, Chipato T, Asmelash A, Rassool M, Kimaiyo S, Shaffer D, Hosseinipour M, Mohapi L, Ssali F, Chibowa M,Amod F, Halvas E, Hogg E, Alston-Smith B, Smith L, Schooley R, Mellors J, Currier J; OCTANE (Optimal Combination Therapy After Nevirapine Exposure) ACTG A5208/OCTANE Study Team. Nevirapine- versus lopinavir/ritonavir-based initial therapy for HIV-1 infection among women in Africa: a randomized trial. PLoS Med. 2012
Adjorlolo-Johnson G, Wahl A, Ramachandran S, Strasser S, Kouakou J, Tindyebwa D, Alons C, Neluheni T, Lee S, Marlink R. Scaling up Pediatric HIV Care and Treatment in Africa: Clinical Site Characteristics Associated with Favorable Service Utilization. J Acquir Immune Defic Syndr. 2012 Sep 5
Raabya Rossenkhan, Vladimir Novitsky, Theresa K. Sebunya, Rosemary Musonda, Berhanu A. Gashe, M. Essex. Viral Diversity and Diversification of Major Non-Structural Genes vif, vpr, vpu, tatexon 1 and rev exon 1 during Primary HIV-1 Subtype C Infection. PLoS One. 2012
Carlson JM, Listgarten J, Pfeifer N, Tan V, Kadie C, Walker BD, Ndung’u T, Shapiro R, Frater J, Brumme ZL, Goulder PJ, Heckerman D. Widespread impact of HLA restriction on immune control and escape pathways of HIV-1. J Virol. 2012 May
Shapiro, Roger L.; Souda, Sajini; Parekh, Natasha; Binda, Kelebogile; Kayembe, Mukendi; Lockman, Shahin; Svab, Petr; Babitseng, Orphinah; Powis, Kathleen; Jimbo, William; Creek, Tracy; Makhema, Joseph; Essex, Max; Roberts, Drucilla J.; Vermund, Sten H. High Prevalence of Hypertension and Placental Insufficiency, but No In Utero HIV Transmission, among Women on HAART with Stillbirths in Botswana. PLoS ONE. 2012
Becquet R, Marston M, Dabis F, Moulton LH, Gray G, Coovadia HM, Essex M, Ekouevi DK, Jackson D, Coutsoudis A, Kilewo C, Leroy V, Wiktor SZ, Nduati R, Msellati P, Zaba B, Ghys PD, Newell ML; UNAIDS Child Survival Group.Children who acquire HIV infection perinatally are at higher risk of early death than those acquiring infection through breastmilk: a meta-analysis. PLoS ONE. 2012
Skinner-Adams TS, Butterworth AS, Porter KA, D’Amico R, Sawe F, Shaffer D, Siika A, Hosseinipour MC, Stringer E, Currier JS, Chipato T, Salata R, Lockman S, Eron JJ, Meshnick SR, McCarthy JS. The Frequency of Malaria Is Similar among Women Receiving either Lopinavir/Ritonavir or Nevirapine-based Antiretroviral Treatment. PLoS ONE. Apr 3
Novitsky, V., Essex, M. Using HIV viral load to guide treatment-for-prevention interventions. Curr Opin HIV AIDS. 2012 Mar 7
Heidari, S., Karim, Q., Auerbach, J., Buitendijk, S., Cahn, P., Curno, M., Hankins, C., Katabira, E., Kippax, S., Marlink, R., Marsh, J., Marusci, A., Nass, H., Montaner, J., Pollitzer, E., Ruiz-Cantero, M., Sherr, L., Sow, P., Squires, K., Wainberg, M. Gender-Sensitive Reporting in Clinical Research. Journal of the International AIDS Soceity. 2012 March 8
Wester, C.W., Stitelman, O.M., Degruttola, V., Bussmann, H., Marlink, R.G., van der Laan, M.J.Effect Modification by Sex and Baseline CD4+ Cell Count Among Adults Receiving Combination Antiretroviral Therapy in Botswana: Results from a Clinical Trial. AIDS Res Hum Retroviruses.2012 Feb 6
Dong, B.J., Zheng, Y., Hughes, M.D., Frymoyer, A., Verotta, D., Lizak, P., Sawe, F., Currier, J.S., Lockman, S., Aweeka, F.T.; for the AIDS Clinical Trials Group Study 5208 Team. Nevirapine (NVP) pharmacokinetics (PK) and risk of rash and hepatitis among HIV-infected Sub-Saharan African Women. AIDS. 2012 Feb 1
Heidari, S., Mofenson, L., Hobbs, C., Cotton, M., Marlink, R., Katabira, E. Unresolved Antiretroviral Treatment Management Issues in HIV-Infected Children. J Acquir Immune Defic Syndr. 2012 Feb 1
Laeyendecker, O., Brookmeyer, R., Mullis, C., Donnell, D., Lingappa, J., Celum, C., Baeten, J.M., Campbell, M.S., Essex, M., de Bruyn, G., Farquhar, C., Quinn, T.C., Eshleman, S. Specificity of four laboratory approaches for cross-sectional HIV incidence determination: Analysis of samples from adults with known non-recent HIV infection from five African countries. AIDS Res Hum Retroviruses. 2012 Jan 29
Lockman, S., Sax, P. Treatment-for-prevention: clinical considerations. Curr Opin HIV AIDS. 2012 Jan 5
Armstrong, K.L., Lee, T.H., Essex, M. The Replicative Fitness Costs of Non-Nucleoside Reverse Transcriptase Inhibitor Drug Resistance Mutations on HIV Subtype C. Antimicrob Agents Chemother. 2011 Mar 14
Agaba. P.A., Digin, E., Makai, R., Apena, L., Agbaji, O.O., Idoko, J.A., Murphy, R., Kanki, P.Clinical characteristics and predictors of mortality in hospitalized HIV-infected Nigerians. J Infect Dev Ctries. May 28 2011
Baeten, J.M., Lingappa, J., Beck., I., Freukel, L., Pepper, G., Wald, A., Fife, K., Were, E., Mugo, N., Sanchez, J., Essex, M., Makhema, J., Kiare, J., Farquhar, C., Corey, L., and Celum, C. Herpes Simplex Virus Type 2 Suppressive Therapy with Acyclovir or Valacyclovir Does Not Select for Specific HIV-1 Resistance in HIV 1/HSV-2 Dually Infected Persons. J. Infect. Dis. 2011 Jan 1
Brown, B.J., Oladokun, R.E., Osinusi, K., Ochigbo, S., Adewole, I.F., Kanki, P. Disclosure of HIV status to infected children in a Nigerian HIV Care Programme. AIDS Care. 2011 Sept 23
Bussmann, H., de la Hoz Gomez, F., Roels, T.H., Wester, C.W., Bodika, S.M., Moyo, S., Taffa, N., Anderson, M.G., Mine, M., Bile, E.C., Yang, C., Mphoyakgosi, K., Lehotzky, E.A., Mlotshwa, B., Mmelesi, M., Seipone, K., Makhema, M.J., Marlink, R.G., Novitsky, V., Essex, M. Prevalence of transmitted HIV drug resistance in Botswana: lessons learned from the HIVDR-Threshold Survey conducted among women presenting for routine antenatal care as part of the 2007 national sentinel survey. AIDS ResHum Retroviruses. 2011 Apr 27
Ciaranello, A.L., Lockman, S., Freedberg, K.A., Hughes, M., Chu, J., Currier, J., Wood, R., Holmes, C.B., Pillay, S., Conradie, F., McIntyre, J., Losina, E., Walensky, R.P. for the CEPAC-International and OCTANE Investigators. First-line antiretroviral therapy after single-dose nevirapine exposure in South Africa: a cost-effectiveness analysis of the OCTANE trial. AIDS. 2011 Feb 20
Cohen, M.S., Chen, Y.Q., McCauley, M., Gamble, T., Hosseinipour, M.C., Kumarasamy, N., Hakim, J.G., Kumwenda, J., Grinsztejn, B., Pilotto, J.H., Godbole, S.V., Mehendale, S., Chariyalertsak, S., Santos, B.R., Mayer, K.H., Hoffman, I.F., Eshleman, S.H., Piwowar-Manning, E., Wang, L., Makhema, J., Mills, L.A., de Bruyn, G., Sanne, I., Eron, J., Gallant, J., Havlir, D., Swindells, S., Ribaudo, H., Elharrar, V., Burns, D., Taha, T.E., Nielsen-Saines, K., Celentano, D., Essex, M., Fleming, T.R.; the HPTN 052 Study Team. Prevention of HIV-1 Infection with Early Antiretroviral Therapy. N Engl J Med. 2011 Aug 11
Dryden-Peterson, S., Shapiro, R.L., Hughes, M.D., Powis, K., Ogwu, A., Moffat, C., Moyo, S., Makhema, J., Essex, M., Lockman, S. Increased Risk of Severe Infant Anemia Following Exposure to Maternal HAART, Botswana. J Acquir Immune Defic Syndr.. 2011 Apr 15
Dryden-Peterson, S., Jayeoba, O., Hughes, M.D., Jibril, H., Keapoletswe, K., Tlale, J., Modise, T.A., Asmelash, A., Moyo, S., van Widenfel,t E., Makhema, J., Essex, M., Shapiro, R.L., Lockman, S. Highly Active Antiretroviral Therapy versus Zidovudine for Prevention of Mother-to-Child Transmission in a Programmatic Setting, Botswana. J Acquir Immune Defic Syndr. 2011 Jul 22
Firnhaber, C., Evans, D., Friedman-Khalili, R., Willliams, S., Michelow, P., Matlhagela, K., Wester, C., Grinsztejn, B., Lockman, S. Seroprevalence of HPV vaccine types 6, 11, 16 and 18 in HIV-infected women from South Africa, Brazil and Botswana. J Clin Virol. 2011 Sep 9
Heidari, S., Mofenson, L.M., Hobbs, C.V., Cotton, M.F., Marlink, R., Katabira, E. Unresolved Antiretroviral Treatment Management Issues in HIV-Infected Children. J Acquir Immune Defic Syndr. 2011 Dec 1
Jayeoba, O., Dryden-Peterson, S., Okui, L., Smeaton, L., Magetse, J., Makori, L., Modikwa, V., Mogodi, M., Plank, R., Lockman, S. Acceptability of Male Circumcision Among Adolescent Boys and their Parents, Botswana. AIDS Behav. 2011 Mar 25
Lin, N.H., Smeaton, L.M., Giguel, F., Novitsky, V., Moyo, S., Mitchell, R.M., Makhema, J., Essex, M., Lockman, S., and Kuritzkes, D.R. Prevalence and clinical associations of CXCR4-using HIV-1 among treatment-naive subtype C-infected women in Botswana. JAIDS. 2011 Feb 21
Lingappa, J.R., Petrovski, S., Kahle, E., Fellay, J., Shianna, K., McElrath, M.J., Thomas, K.K., Baeten, J.M., Celum, C., Wald, A., de Bruyn, G., Mullins, J.I., Nakku-Joloba, E., Farquhar, C., Essex, M., Donnell, D., Kiarie, J., Haynes, B., Goldstein, D.; for the Partners in Prevention HSV/HIV Transmission Study Team .Genomewide Association Study for Determinants of HIV-1 Acquisition and Viral Set Point in HIV-1 Serodiscordant Couples with Quantified Virus Exposure. PLoS One. 2011 Dec 12
Matthews, L.T., Ribaudo, H.J., Parekh, N.K., Chen, J.Y., Binda, K., Ogwu, A., Makhema, J., Souda, S., Lockman, S., Essex, M., Shapiro, R.L. Birth weight for gestational age norms for a large cohort of infants born to HIV-negative women in Botswana compared with norms for U.S-born black infants. BMC Pediatr. 2011 Dec 16
Macleod IJ, O’Donnell B, Moyo S, Lockman S, Shapiro RL, Kayembe M, van Widenfelt E, Makhema J, Essex M, Wester C. Prevalence of HPV Genotypes and Associated Cervical Squamous Intraepithelial Lesions in HIV+ Women in Botswana. J Med Virol. 2011
Novitsky, V., Wang, R., Margolin, L., Baca, J., Rossenkhan, R., Moyo, S., van Widenfelt, E., and Essex, M. Transmission of Single and Multiple Viral Variants in Primary HIV-1 Subtype C Infection. PLoS One. 2011 Feb 9
Novitsky, V., Ndung’u, T., Wang, R., Bussmann, H., Chonco, F., Makhema, J., De Gruttola, V., Walker, B.D., Essex, M. Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection. AIDS. 2011 Apr 18
Novitsky, V., Wang, R., Baca, J., Margolin, L., McLane, MF., Moyo, S., van Widenfelt, E., Makhema, J., Essex, M. Evolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection. Virology. 2011 Oct 17
Parekh, N., Ribaudo, H., Souda, S., Chen, J., Mmalane, M., Powis, K., Essex, M., Makhema, J., Shapiro, R.L. Risk factors for very preterm delivery and delivery of very-small-for-gestational-age infants among HIV-exposed and HIV-unexposed infants in Botswana. Int J Gynaecol Obstet. 2011 Jul 16
Porter, K.A., Cole, S.R., Eron, J.J. Jr, Zheng, Y., Hughes, M.D., Lockman, S., Poole, C., Skinner-Adams, T.S., Hosseinipour, M., Shaffer, D., D’Amico, R., Sawe, F.K., Siika, A., Stringer, E., Currier, J.S., Chipato, T., Salata, R., McCarthy, J.S., Meshnick, S.R. HIV-1 protease inhibitors and clinical malaria: A secondary analysis of ACTG A5208. Antimicrob Agents Chemother. 2011 Nov 28
Powis, K.M., Smeaton, L., Ogwu, A., Lockman, S. Dryden-Peterson, S., van Widenfelt, E., Leidner, J., Makhema, J., Essex, M., and Shapiro, R.L. Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana. JAIDS. 2011
Powis, K.M., Kitch, D., Ogwu, A., Hughes, M.D., Lockman, S., Leidner, J., van Widenfelt, E., Moffat, C., Moyo, S., Makhema, J., Essex, M., Shapiro, R.L. Increased Risk of Preterm Delivery Among HIV-Infected Women Randomized to Protease Versus Nucleoside Reverse Transcriptase Inhibitor-Based HAART During Pregnancy. J Infect Dis. 2011 Aug
Rawizza, H.E., Chaplin, B., Meloni, S.T., Eisen, G., Rao, T., Sankalé, J.L., Dieng-Sarr, A., Agbaj,i O., Onwujekwe, D.I., Gashau, W., Nkado, R., Ekong, E., Okonkwo, P., Murphy, R.L., Kanki, P.J.; for the APIN PEPFAR Team. Immunologic Criteria Are Poor Predictors of Virologic Outcome: Implications for HIV Treatment Monitoring in Resource-Limited Settings. Clin Infect Dis. 2011 Dec
Wester, C.W., Koethe, J.R., Shepherd, B.E., Stinnette, S.E., Rebeiro, P.F., Kipp, A..M., Hong, H., Bussmann, H., Gaolathe, T., McGowan, C.C., Sterling, T.R., Marlink, R.G Non-AIDS Defining Events Among HIV-1 Infected Adults Receiving Combination Antiretroviral Therapy In Urban Settings in Sub-Saharan Africa and the United States. AIDS. 2011 May 12
Write, J.K., Novitsky, V., Brockman, M.A., Brumme, Z.L., Brumme, C.J., Carlson, J.M., Heckerman, D., Wang, B., Losina, E., Leshwedi, M., van der Stok, M., Maphumulo, L., Mkhwanazi, N., Chonoc, F., Goulder, P.J.R., Essex, M., Walker, B.D., and Ndung’u, T. Influence of Gag-Protease-Mediated Replication Capacity on Disease Progression in Individuals Recently Infected with HIV-1 Subtype C. J of Virology. 2011 Feb 2
Celum, C., Wald, A., Lingappa, J.R., Magaret, A.S., Wang, R.S., Mugo, N., Mujugira, A., Baeten, J.M., Mullins, J.I., Hughes, J.P., Bukusi, E.A., Cohen, C.R., Katabira, E., Ronald, A., Kiarie, J., Farquhar, C., Stewart, G.J., Makhema, J., Essex, M., Were, E., Fife, K.H., de Bruyn, G., Gray, G.E., McIntyre, J.A., Manongi, R., Kapiga, S., Coetzee, D., Allen, S., Inambao, M., Kayitenkore, K., Karita, E., Kanweka, W., Delany, S., Rees, H., Vwalika, B., Stevens, W., Campbell, M.S., Thomas, K.K., Coombs, R.W., Morrow, R., Whittington, W.L.H., McElrath, M.J., Barnes, L., Ridzon, R., and Corey, L., for the Partners in Prevention HSV/HIV Transmission Study Team. Acyclovir and Transmission of HIV-1 from Persons Infected with HIV-1 and HSV-2. N Engl J Med 2010
Chen, J.Y., Ogwu, A.C., Svab, P., Lockman, S., Moffat, H.J., Gaolathe, T., Moilwa, S., Størdal, K., Dryden-Peterson, S., Moffat, C., Makhema, J., Essex, M., and Shapiro, R.L. Antiretroviral Treatment Initiation among HIV-Infected Pregnant Women with Low CD4+ Cell Counts in Gaborone, Botswana. J. Acquir. Immune Defic. Syndr 2010
Chigwedere, P. and Essex, M. AIDS Denialism and Public Health Practice. AIDS Behav. 2010. 2010
Kebaabetswe, P., Ndase, P., Mujugira, A., Sekoto, T., Ntshimane, M., Owor, A., Makhema, J., Thior, I., and Essex, M. Perceptions of couple HIV counseling and testing in Botswana: A stakeholder analysis. Patient Educ. Couns 2010
Lin, N.H., Negusse, D.M., Beroukhim, R., Giguel, F., Lockman, S., Essex, M., and Kuritzkes, D.R. The Design and Validation of a Novel Phenotypic Assay to Determine HIV-1 Coreceptor Usage of Clinical Isolates. J Virol Methods 2010
Lingappa., J.R., Baeten, J.M., Wald, A., Hughes, J.P., Thomas, K.T., Mujugira, A., Mugo, N., Bukusi, E.A., Cohen, C.R., Katabira, E., Ronald, A., Kiarie, J., Farquhar, C., Steward, G.J., Makehma, J., Essex, M., Were, E., Fife, K.H., de Bruyen, G., Gray, G.E., McIntyre, J.A., Manongi, R., Kapiga, S., Coetzee, D., Allen, S., Inambao, M., Kayitenkore, K., Karita, E., Kanweka, W., Delany, S., Rees, H., Vwalika, B., Magaret, A.S., Wang, R.S., Kidoguchi, L., Barnes, L., Ridzon, R., Corey, L., and Celum, C. for the Partners in Prevention HSV/HIV Transmission Study Team.Daily aciclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial. The Lancet. 2010
Lingappa, J.R., Hughes, J.P., Wang, R.S., Baeten, J.M., Celum, C., Gray, G.E., Stevens, W., Donnell, D., Campbell, M.S., Farquhar, C., Essex, M., Mullins, J.I., Coombs, R.W., Rees, H., Corey, L., and Wald, A. for the Partners in Prevention HSV/HIV Transmission Study Team.Estimating the Impact of Plasma HIV-1 RNA Reductions on Heterosexual HIV-1 Transmission Risk. PLoS One Sept 13 2010
Lockman, S., Hughes, M.D., McIntyre, J., Zheng, Y., Chipato, T., Conradie, F., Sawe, F., Asmelash, A., Hosseinipour, M.C., Mohapi, L., Stringer, E., Mngqibisa, R., Siika, A., Atwine, D., Hakim, J., Shaffer, D., Kanyama, C., Wools-Kaloustian, K., Salata, R.A., Hogg, E., Alston-Smith, B., Walawander, A., Purcelle-Smith, E., Eshleman, S., Rooney, J., Rahim, S., Mellors, J.W., Schooley, R.T., Currier, J.S.; OCTANE A5208 Study Team. Antiretroviral therapies in women after single-dose nevirapine exposure. N Engl J Med. 2010 Oct 14 2010
MacLeod, I.J., Rowley, C.F., Essex, M., and Lockman, S. Minor Resistant Variants in Nevirapine-Exposed Infants May Predict Virologic Failure on Nevirapine-Containing ART. J. Clin. Virol. 2010.
Novitsky, V., Wang, R., Bussmann, H., Lockman, S., Baum, M., Shapiro, R., Thior, I., Wester, C., Wester, C.W., Ogwu, A., Asmelash, A., Musonda, R., Campa, A., Moyo, S., van Widenfelt, E., Mine, M., Moffat, C., Mmalane, M., Makhema, J., Marlink, R., Gilbert, P., Seage, G.R. 3rd, DeGruttola, V., and Essex, M. HIV-1 Subtype C Infected Individuals Maintaining High Viral Load as Potential Targets for the “Test-and-Treat” Approach to Reduce HIV Transmission. PloS One 2010
Novitsky, V., Wang, R., Lagakos, S., and Essex, M. HIV-1 Subtype C Phylodynamics in the Global Epidemic. Viruses 2010
Novitsky, V., Wang, R., Margolin, L., Baca, J., Moyo, S., Musonda, R., and Essex, M. Dynamics and Timing of in Vivo Mutations at Gag Residue 242 during Primary HIV-1 Subtype C Infection. Virology. 2010
Plank, R.M., Makhema, J., Kebaabetswe, P., Hussein, F., Leseidi, C., Halperinm D., Bassil, B., Shapiro, R., Lockman, S. Acceptability of infant male circumcision as part of HIV prevention and male reporductive health efforts in Gaborone, Botswana, and surrounding areas. AIDS Behav. Oct 2010
Rowley, C.F., Boutwell, C.L., Lee, E.J., MacLeod, I.J., Ribaudo, H.J., Essex, M, and Lockman, S.Ultrasensitive Detection of Minor Drug-Resistant Variants for HIV after Nevirapine Exposure Using Allele-Specific PCR: Clinical Significance. AIDS Res. Hum. Retroviruses 2010
Shapiro, R., Hughes, M., Ogwu, A., Kitch, D., Lockman, S., Moffat, C., Makhema, J., Moyo, S., Thior, I., McIntosh, K., van Widenfelt, E., Leidner, J., Powis, K., Asmelash, A., Tumbare, E., Zwerski, S., Sharma, U., Handelsman, E., Mburu, K., Jayeoba, O., Moko, E., Souda, S., Lubega, E., Akhtar, M., Wester, C., Snowden, W., Martinez-Tristani, M., Mazhani, L., Essex, M.Antiretroviral Regimens in Pregnancy and Breast-Feeding in Botswana. N Engl J Med. 2010
Shapiro, R.L., Lockman, S. Mortality among HIV-exposed infants: the first and final frontier. Clin Infect Dis. Feb 2010
Teeravechyan, S., Essex, M., and Lee, T.H. Conserved Determinants of Enhanced CCR5 Binding in the Human Immunodeficiency Virus Subtype D Envelope Third Variable Loop. AIDS Res. Hum. Retroviruses 2010
Wester, C.W., Thomas, A.M., Bussmann, H., Moyo, S., Makhema, J.M., Gaolathe, T.,Novitsky, V., Essex, M., DeGruttola, V., and Marlink, R.G. Non-nucleoside reverse transcriptase inhibitor outcomes among combination antiretroviral therapy-treated adults in Botswana. AIDS. 2010
Armstrong, K.L., Lee, TH, and Essex, M. Replicative Capacity Differences of Thymidine Analog Resistance Mutations in Subtype B and C Human Immunodeficiency Virus Type 1. J. Virol. 2009
Boutwell, C.L., Rowley, C.F., and Essex, M. Reduced Viral Replication Capacity of HIV-1 Subtype C Caused by CTL Escape Mutations in HLA-B57 Epitopes of Capsid Protein. J. Virol. 2009
Bussmann, H., Wester, C.W., Thomas, A., Novitsky, V., Okezie, R., Muzenda, T., Gaolathe, T., Ndwapi, N., Mawoko, N., Widenfelt, E., Moyo, S., Musonda, R., Mine, M., Makhema, J., Moffat, H., Essex, M., DeGruttola, V., and Marlink, R.G. Response to Zidovudine/Didanosine-Containing Combination Antiretroviral Therapy Among HIV-1 Subtype C-Infected Adults in Botswana: Two-Year Outcomes from a Randomized Clinical Trial. J Acquir Immune Defic Syndr. 2009
Chen, J.Y., Ogwu, A.C., Svab, P., Lockman, S., Moffat, H.J., Gaolathe, T., Moilwa, S., Størdal, K., Dryden-Peterson, S., Moffat, C., Makhema, J., Essex, M., and Shapiro, R.L. Antiretroviral Treatment Initiation among HIV-Infected Pregnant Women with Low CD4+ Cell Counts in Gaborone, Botswana. J Acquir Immune Defic Syndr. 2009
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