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Vaccine Think Tank

Symposium Series on Vaccine Solutions for Developing Countries

A Report of HAI

October 4–7, 1999
MIT Endicott House
Dedham, Massachusetts USA

Sponsors
HAI
United States Military HIV Research Program

Cosponsors
Albert B. Sabin Vaccine Institute at Georgetown University
Fogarty International Center
International AIDS Vaccine Initiative
Wyeth–Lederle Vaccines

HIV Vaccines for Developing Countries: Prioritizing Vaccine Candidates for Human Trials was sponsored by HAI and the United States Military HIV Research Program, with cosponsorship provided by Albert B. Sabin Vaccine Institute at Georgetown University, Fogarty International Center of the United States National Institutes of Health, International AIDS Vaccine Initiative, and Wyeth-Lederle Vaccines.

This report was written by Jason Blackard, Thumbi Ndung’u, and Fredrik Vannberg and is based on the presentations and discussions that took place at the meeting. The report was coordinated by Molly Holme and produced by HAI staff. For more information, contact HAI at 651 Huntington Avenue, Boston, Massachusetts 02115 USA (phone: +1-617-432-4400 fax: +1-617-432-4545 email: hai@hsph.harvard.edu.

This report was produced by HAI.

TABLE OF CONTENTS

Overview of HIV Vaccine Development to Date
Requirements for HIV Vaccines Used in Developing Countries
Molecular Epidemiology and HIV Vaccinology
Existing Vaccine Choices
Lessons From Asia
Lessons From Eastern Africa
Lessons From Southern Africa
Lessons From Western Africa
Lessons From South America and the Caribbean
Elements of Success and Failure
Feasibility, Funding, and the Future
Concluding Thoughts and a Call to Action

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